# Women's Angiographic Vitamin and Estrogen Trial (WAVE)

> **NCT00000555** · PHASE3 · COMPLETED · sponsor: **National Heart, Lung, and Blood Institute (NHLBI)**

## Conditions studied

- Cardiovascular Diseases
- Coronary Arteriosclerosis
- Coronary Disease
- Heart Diseases
- Myocardial Ischemia
- Postmenopause

## Interventions

- **DRUG:** estrogen replacement therapy
- **DRUG:** estrogens, conjugated
- **DRUG:** progesterone
- **DRUG:** hormone replacement therapy
- **DRUG:** supplementation, food
- **DRUG:** ascorbic acid
- **DRUG:** vitamin e

## Key facts

- **NCT ID:** NCT00000555
- **Lead sponsor:** National Heart, Lung, and Blood Institute (NHLBI)
- **Sponsor class:** NIH
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1996-08
- **Primary completion:** —
- **Final completion:** 2003-05
- **Target enrollment:** — (—)
- **Last updated:** 2016-07-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00000555

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00000555, "Women's Angiographic Vitamin and Estrogen Trial (WAVE)". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT00000555. Licensed CC0.

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