# The Role of Hormones in Postpartum Mood Disorders

> **NCT00001481** · PHASE2 · COMPLETED · sponsor: **National Institute of Mental Health (NIMH)** · enrollment: 74 (actual)

## Conditions studied

- Postpartum Depression

## Interventions

- **DRUG:** Estradiol
- **OTHER:** Placebo
- **DRUG:** Progesterone
- **DRUG:** leuprolide acetate

## Key facts

- **NCT ID:** NCT00001481
- **Lead sponsor:** National Institute of Mental Health (NIMH)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1996-04-26
- **Primary completion:** 2024-10-25
- **Final completion:** 2024-10-25
- **Target enrollment:** 74 (ACTUAL)
- **Last updated:** 2025-12-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00001481

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00001481, "The Role of Hormones in Postpartum Mood Disorders". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT00001481. Licensed CC0.

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