# Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors

> **NCT00002594** · PHASE2 · COMPLETED · sponsor: **Children's Oncology Group** · enrollment: 31 (actual)

## Conditions studied

- Brain Tumor
- Central Nervous System Tumor

## Interventions

- **BIOLOGICAL:** Sargramostim
- **DRUG:** cyclophosphamide
- **DRUG:** melphalan
- **PROCEDURE:** autologous bone marrow transplantation
- **PROCEDURE:** bone marrow ablation with stem cell support
- **PROCEDURE:** peripheral blood stem cell transplantation

## Key facts

- **NCT ID:** NCT00002594
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1994-09
- **Primary completion:** 2003-09
- **Final completion:** 2007-03
- **Target enrollment:** 31 (ACTUAL)
- **Last updated:** 2014-07-24

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00002594

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00002594, "Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT00002594. Licensed CC0.

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