# Combination Chemotherapy in Treating Pediatric Patients With Advanced-Stage Large Cell Lymphoma

> **NCT00002618** · PHASE3 · COMPLETED · sponsor: **Children's Oncology Group** · enrollment: 242 (estimated)

## Conditions studied

- Lymphoma

## Interventions

- **BIOLOGICAL:** filgrastim
- **DRUG:** cytarabine
- **DRUG:** doxorubicin hydrochloride
- **DRUG:** leucovorin calcium
- **DRUG:** mercaptopurine
- **DRUG:** methotrexate
- **DRUG:** prednisone
- **DRUG:** vincristine sulfate
- **RADIATION:** low-LET cobalt-60 gamma ray therapy
- **RADIATION:** low-LET electron therapy
- **RADIATION:** low-LET photon therapy

## Key facts

- **NCT ID:** NCT00002618
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1994-12
- **Primary completion:** 2000-09
- **Final completion:** 2006-09
- **Target enrollment:** 242 (ESTIMATED)
- **Last updated:** 2014-07-24

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00002618

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00002618, "Combination Chemotherapy in Treating Pediatric Patients With Advanced-Stage Large Cell Lymphoma". Retrieved via AI Analytics 2026-07-25 from https://api.ai-analytics.org/clinical/NCT00002618. Licensed CC0.

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