# Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia

> **NCT00002658** · PHASE3 · UNKNOWN · sponsor: **Medical Research Council** · enrollment: 2000 (estimated)

## Conditions studied

- Leukemia
- Neutropenia

## Interventions

- **BIOLOGICAL:** filgrastim
- **DRUG:** amsacrine
- **DRUG:** cyclophosphamide
- **DRUG:** cytarabine
- **DRUG:** daunorubicin hydrochloride
- **DRUG:** etoposide
- **DRUG:** idarubicin
- **DRUG:** mitoxantrone hydrochloride
- **DRUG:** thioguanine
- **DRUG:** tretinoin
- **PROCEDURE:** allogeneic bone marrow transplantation
- **PROCEDURE:** autologous bone marrow transplantation
- **PROCEDURE:** peripheral blood stem cell transplantation
- **RADIATION:** radiation therapy

## Key facts

- **NCT ID:** NCT00002658
- **Lead sponsor:** Medical Research Council
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 1994-01
- **Primary completion:** —
- **Final completion:** —
- **Target enrollment:** 2000 (ESTIMATED)
- **Last updated:** 2013-12-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00002658

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00002658, "Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT00002658. Licensed CC0.

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