# Standard Chemotherapy Compared With High-Dose Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer

> **NCT00002755** · PHASE3 · COMPLETED · sponsor: **Scottish Cancer Therapy Network** · enrollment: 600 (estimated)

## Conditions studied

- Breast Cancer

## Interventions

- **BIOLOGICAL:** filgrastim
- **DRUG:** CMF regimen
- **DRUG:** cyclophosphamide
- **DRUG:** doxorubicin hydrochloride
- **DRUG:** fluorouracil
- **DRUG:** methotrexate
- **DRUG:** tamoxifen citrate
- **DRUG:** thiotepa
- **PROCEDURE:** autologous bone marrow transplantation
- **PROCEDURE:** peripheral blood stem cell transplantation
- **RADIATION:** low-LET cobalt-60 gamma ray therapy
- **RADIATION:** low-LET electron therapy
- **RADIATION:** low-LET photon therapy

## Key facts

- **NCT ID:** NCT00002755
- **Lead sponsor:** Scottish Cancer Therapy Network
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1995-11
- **Primary completion:** —
- **Final completion:** 1999-06
- **Target enrollment:** 600 (ESTIMATED)
- **Last updated:** 2013-11-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00002755

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00002755, "Standard Chemotherapy Compared With High-Dose Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00002755. Licensed CC0.

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