# Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia

> **NCT00002785** · PHASE2 · COMPLETED · sponsor: **Children's Oncology Group**

## Conditions studied

- Leukemia

## Interventions

- **BIOLOGICAL:** filgrastim
- **DRUG:** asparaginase
- **DRUG:** cyclophosphamide
- **DRUG:** cyclosporine
- **DRUG:** cytarabine
- **DRUG:** daunorubicin hydrochloride
- **DRUG:** dexamethasone
- **DRUG:** etoposide
- **DRUG:** leucovorin calcium
- **DRUG:** mercaptopurine
- **DRUG:** mesna
- **DRUG:** methotrexate
- **DRUG:** methylprednisolone
- **DRUG:** pegaspargase
- **DRUG:** prednisone
- **DRUG:** therapeutic hydrocortisone
- **DRUG:** vincristine sulfate
- **PROCEDURE:** allogeneic bone marrow transplantation
- **RADIATION:** low-LET cobalt-60 gamma ray therapy
- **RADIATION:** low-LET photon therapy

## Key facts

- **NCT ID:** NCT00002785
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1996-07
- **Primary completion:** 2000-08
- **Final completion:** 2007-03
- **Target enrollment:** — (—)
- **Last updated:** 2014-07-24

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00002785

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00002785, "Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT00002785. Licensed CC0.

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