# High-Intensity, Brief-Duration Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia

> **NCT00002865** · PHASE2 · COMPLETED · sponsor: **Wake Forest University Health Sciences** · enrollment: 25 (actual)

## Conditions studied

- Leukemia

## Interventions

- **BIOLOGICAL:** filgrastim
- **DRUG:** cyclophosphamide
- **DRUG:** cytarabine
- **DRUG:** dexamethasone
- **DRUG:** doxorubicin hydrochloride
- **DRUG:** etoposide
- **DRUG:** ifosfamide
- **DRUG:** leucovorin calcium
- **DRUG:** mesna
- **DRUG:** methotrexate
- **DRUG:** therapeutic hydrocortisone
- **DRUG:** vincristine sulfate
- **RADIATION:** low-LET cobalt-60 gamma ray therapy
- **RADIATION:** low-LET photon therapy

## Key facts

- **NCT ID:** NCT00002865
- **Lead sponsor:** Wake Forest University Health Sciences
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1995-04
- **Primary completion:** 2000-06
- **Final completion:** 2001-08
- **Target enrollment:** 25 (ACTUAL)
- **Last updated:** 2018-08-10

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00002865

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00002865, "High-Intensity, Brief-Duration Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT00002865. Licensed CC0.

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