# Chemotherapy With or Without Total-Body Irradiation Prior to Bone Marrow Transplantation in Treating Children With Acute Lymphoblastic Leukemia

> **NCT00002961** · PHASE3 · TERMINATED · sponsor: **Children's Hospital of Philadelphia** · enrollment: 43 (actual)

## Conditions studied

- Leukemia

## Interventions

- **DRUG:** cyclophosphamide
- **DRUG:** cyclosporine
- **DRUG:** etoposide
- **DRUG:** methotrexate
- **PROCEDURE:** allogeneic bone marrow transplantation
- **RADIATION:** Total Body Irradiation
- **DRUG:** Busulfan
- **DRUG:** Mesna
- **RADIATION:** Radiation

## Key facts

- **NCT ID:** NCT00002961
- **Lead sponsor:** Children's Hospital of Philadelphia
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 1995-10
- **Primary completion:** 2001-02
- **Final completion:** 2001-02
- **Target enrollment:** 43 (ACTUAL)
- **Why stopped:** poor accrual
- **Last updated:** 2013-10-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00002961

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00002961, "Chemotherapy With or Without Total-Body Irradiation Prior to Bone Marrow Transplantation in Treating Children With Acute Lymphoblastic Leukemia". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT00002961. Licensed CC0.

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