# Paclitaxel and Radiation Therapy Plus Chemoprotection With Amifostine in Treating Patients With Stage III or Stage IV Head and Neck Cancer

> **NCT00003193** · PHASE1,PHASE2 · COMPLETED · sponsor: **Massachusetts General Hospital** · enrollment: 37 (estimated)

## Conditions studied

- Head and Neck Cancer
- Oral Complications

## Interventions

- **DRUG:** amifostine trihydrate
- **DRUG:** paclitaxel
- **PROCEDURE:** conventional surgery
- **RADIATION:** radiation therapy

## Key facts

- **NCT ID:** NCT00003193
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1998-01
- **Primary completion:** 2005-09
- **Final completion:** 2005-09
- **Target enrollment:** 37 (ESTIMATED)
- **Last updated:** 2012-12-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00003193

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00003193, "Paclitaxel and Radiation Therapy Plus Chemoprotection With Amifostine in Treating Patients With Stage III or Stage IV Head and Neck Cancer". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT00003193. Licensed CC0.

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