# Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma

> **NCT00003776** · PHASE2 · COMPLETED · sponsor: **Memorial Sloan Kettering Cancer Center**

## Conditions studied

- Sarcoma

## Interventions

- **BIOLOGICAL:** filgrastim
- **DRUG:** cisplatin
- **DRUG:** doxorubicin hydrochloride
- **DRUG:** ifosfamide
- **DRUG:** leucovorin calcium
- **DRUG:** methotrexate
- **DRUG:** trimetrexate glucuronate
- **PROCEDURE:** surgical procedure

## Key facts

- **NCT ID:** NCT00003776
- **Lead sponsor:** Memorial Sloan Kettering Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1998-12
- **Primary completion:** 2000-03
- **Final completion:** 2000-03
- **Target enrollment:** — (—)
- **Last updated:** 2013-06-21

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00003776

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00003776, "Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00003776. Licensed CC0.

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