# Sertraline for Alcohol Dependence and Depression

> **NCT00004554** · PHASE4 · COMPLETED · sponsor: **University of Pennsylvania** · enrollment: 171 (actual)

## Conditions studied

- Alcoholism
- Depression

## Interventions

- **DRUG:** naltrexone (Revia)
- **DRUG:** sertraline (Zoloft)
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT00004554
- **Lead sponsor:** University of Pennsylvania
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2000-01
- **Primary completion:** 2005-08
- **Final completion:** 2006-02
- **Target enrollment:** 171 (ACTUAL)
- **Last updated:** 2015-10-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00004554

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00004554, "Sertraline for Alcohol Dependence and Depression". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT00004554. Licensed CC0.

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