# Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone

> **NCT00004645** · PHASE3 · UNKNOWN · sponsor: **National Institute of Neurological Disorders and Stroke (NINDS)** · enrollment: 22 (—)

## Conditions studied

- Acute Disseminated Encephalomyelitis
- Devic's Syndrome
- Marburg's Variant of Multiple Sclerosis
- Balo's Concentric Sclerosis
- Acute Transverse Myelitis

## Interventions

- **PROCEDURE:** Plasma exchange

## Key facts

- **NCT ID:** NCT00004645
- **Lead sponsor:** National Institute of Neurological Disorders and Stroke (NINDS)
- **Sponsor class:** NIH
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 1995-01
- **Primary completion:** —
- **Final completion:** —
- **Target enrollment:** 22 (—)
- **Last updated:** 2005-06-24

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00004645

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00004645, "Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00004645. Licensed CC0.

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