# Phase II Randomized Study of Early Surgery Vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment

> **NCT00004758** · PHASE2 · COMPLETED · sponsor: **National Center for Research Resources (NCRR)** · enrollment: 30 (—)

## Conditions studied

- Spasms, Infantile
- Epilepsy

## Interventions

- **DRUG:** carbamazepine
- **DRUG:** corticotropin
- **DRUG:** nitrazepam
- **DRUG:** pyridoxine
- **DRUG:** valproic acid
- **PROCEDURE:** Surgery

## Key facts

- **NCT ID:** NCT00004758
- **Lead sponsor:** National Center for Research Resources (NCRR)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1993-11
- **Primary completion:** —
- **Final completion:** —
- **Target enrollment:** 30 (—)
- **Last updated:** 2005-06-24

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00004758

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00004758, "Phase II Randomized Study of Early Surgery Vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00004758. Licensed CC0.

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