# Combination Chemotherapy and Interferon Alfa Followed by Surgery and/or Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer

> **NCT00004897** · PHASE2 · TERMINATED · sponsor: **Northwestern University**

## Conditions studied

- Esophageal Cancer

## Interventions

- **BIOLOGICAL:** recombinant interferon alfa
- **DRUG:** cisplatin
- **DRUG:** fluorouracil
- **DRUG:** hydroxyurea
- **DRUG:** leucovorin calcium
- **PROCEDURE:** conventional surgery
- **RADIATION:** radiation therapy

## Key facts

- **NCT ID:** NCT00004897
- **Lead sponsor:** Northwestern University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 1999-10
- **Primary completion:** 2007-07
- **Final completion:** 2007-11
- **Target enrollment:** — (—)
- **Why stopped:** Institutional Review Board requested termination - all patients deceased and no new accrual.
- **Last updated:** 2012-06-12

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00004897

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00004897, "Combination Chemotherapy and Interferon Alfa Followed by Surgery and/or Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT00004897. Licensed CC0.

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