# Removal of T Cells to Prevent Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation

> **NCT00005641** · PHASE2 · TERMINATED · sponsor: **H. Lee Moffitt Cancer Center and Research Institute**

## Conditions studied

- Chronic Myeloproliferative Disorders
- Graft Versus Host Disease
- Leukemia
- Multiple Myeloma and Plasma Cell Neoplasm
- Myelodysplastic Syndromes

## Interventions

- **BIOLOGICAL:** anti-thymocyte globulin
- **DRUG:** busulfan
- **DRUG:** cyclophosphamide
- **DRUG:** cyclosporine
- **DRUG:** leucovorin calcium
- **DRUG:** methotrexate
- **DRUG:** methylprednisolone
- **PROCEDURE:** allogeneic bone marrow transplantation
- **PROCEDURE:** in vitro-treated bone marrow transplantation
- **RADIATION:** radiation therapy

## Key facts

- **NCT ID:** NCT00005641
- **Lead sponsor:** H. Lee Moffitt Cancer Center and Research Institute
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 1997-09
- **Primary completion:** 2000-09
- **Final completion:** 2000-09
- **Target enrollment:** — (—)
- **Why stopped:** low study accrual
- **Last updated:** 2012-12-11

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00005641

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00005641, "Removal of T Cells to Prevent Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT00005641. Licensed CC0.

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