# Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma

> **NCT00005803** · PHASE1,PHASE2 · COMPLETED · sponsor: **Fred Hutchinson Cancer Center** · enrollment: 76 (actual)

## Conditions studied

- Prolymphocytic Leukemia
- Recurrent Adult Hodgkin Lymphoma
- Recurrent Childhood Hodgkin Lymphoma
- Recurrent Childhood Non-Hodgkin Lymphoma
- Recurrent Chronic Lymphocytic Leukemia
- Recurrent Non-Hodgkin Lymphoma
- Recurrent Small Lymphocytic Lymphoma
- Refractory Childhood Hodgkin Lymphoma
- Refractory Chronic Lymphocytic Leukemia
- Refractory Hodgkin Lymphoma
- Refractory Non-Hodgkin Lymphoma
- Refractory Small Lymphocytic Lymphoma
- T-Cell Chronic Lymphocytic Leukemia
- T-Cell Prolymphocytic Leukemia

## Interventions

- **PROCEDURE:** Autologous Hematopoietic Stem Cell Transplantation
- **PROCEDURE:** Autologous-Allogeneic Tandem Hematopoietic Stem Cell Transplantation
- **DRUG:** Carmustine
- **DRUG:** Cyclophosphamide
- **DRUG:** Cyclosporine
- **DRUG:** Cytarabine
- **DRUG:** Etoposide
- **DRUG:** Fludarabine Phosphate
- **OTHER:** Laboratory Biomarker Analysis
- **DRUG:** Melphalan
- **DRUG:** Mycophenolate Mofetil
- **PROCEDURE:** Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
- **PROCEDURE:** Peripheral Blood Stem Cell Transplantation
- **BIOLOGICAL:** Therapeutic Autologous Lymphocytes
- **RADIATION:** Total-Body Irradiation

## Key facts

- **NCT ID:** NCT00005803
- **Lead sponsor:** Fred Hutchinson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1999-09
- **Primary completion:** 2016-01
- **Final completion:** 2018-10
- **Target enrollment:** 76 (ACTUAL)
- **Last updated:** 2020-01-29

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00005803

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00005803, "Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT00005803. Licensed CC0.

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