# Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor

> **NCT00006461** · PHASE3 · COMPLETED · sponsor: **Children's Oncology Group** · enrollment: 82 (actual)

## Conditions studied

- Untreated Childhood Medulloblastoma
- Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor

## Interventions

- **DRUG:** cisplatin
- **DRUG:** cyclophosphamide
- **DRUG:** vincristine sulfate
- **DRUG:** etoposide
- **PROCEDURE:** therapeutic conventional surgery
- **RADIATION:** 3-dimensional conformal radiation therapy

## Key facts

- **NCT ID:** NCT00006461
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2000-10
- **Primary completion:** 2007-09
- **Final completion:** —
- **Target enrollment:** 82 (ACTUAL)
- **Last updated:** 2013-08-09

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00006461

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00006461, "Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT00006461. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
