# Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal Methotrexate

> **NCT00018967** · NA · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 10 (estimated)

## Conditions studied

- Neurotoxicity
- Unspecified Adult Solid Tumor, Protocol Specific
- Unspecified Childhood Solid Tumor, Protocol Specific

## Interventions

- **DRUG:** glucarpidase

## Key facts

- **NCT ID:** NCT00018967
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1993-11
- **Primary completion:** 2007-04
- **Final completion:** —
- **Target enrollment:** 10 (ESTIMATED)
- **Last updated:** 2015-04-30

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00018967

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00018967, "Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal Methotrexate". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT00018967. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*