Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma

NCT00023998 · clinicaltrials.gov ↗

PHASE2

Phase

COMPLETED

Status

80

Enrollment

NIH

Sponsor class

Conditions

Metastatic Osteosarcoma

Interventions

DRUG: doxorubicin hydrochloride
DRUG: cisplatin
DRUG: methotrexate
DRUG: leucovorin calcium
BIOLOGICAL: filgrastim
PROCEDURE: therapeutic conventional surgery
RADIATION: radiation therapy
DRUG: etoposide
DRUG: ifosfamide
BIOLOGICAL: trastuzumab
OTHER: laboratory biomarker analysis

Sponsor

National Cancer Institute (NCI)