Combination Chemotherapy Followed By Donor Bone Marrow or Umbilical Cord Blood Transplant in Treating Children With Newly Diagnosed Juvenile Myelomonocytic Leukemia

NCT00025038 · clinicaltrials.gov ↗

PHASE2

Phase

COMPLETED

Status

100

Enrollment

NIH

Sponsor class

Conditions

Juvenile Myelomonocytic Leukemia

Interventions

DRUG: tipifarnib
DRUG: isotretinoin
DRUG: fludarabine phosphate
DRUG: cytarabine
RADIATION: radiation therapy
DRUG: cyclophosphamide
BIOLOGICAL: anti-thymocyte globulin
PROCEDURE: allogeneic bone marrow transplantation
PROCEDURE: double-unit umbilical cord blood transplantation
PROCEDURE: umbilical cord blood transplantation
OTHER: laboratory biomarker analysis

Sponsor

National Cancer Institute (NCI)