# Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer

> **NCT00027820** · PHASE1,PHASE2 · COMPLETED · sponsor: **Fred Hutchinson Cancer Center** · enrollment: 106 (actual)

## Conditions studied

- Adult Acute Myeloid Leukemia in Remission
- Childhood Acute Lymphoblastic Leukemia in Remission
- Childhood Acute Myeloid Leukemia in Remission
- Childhood Myelodysplastic Syndrome
- Childhood Renal Cell Carcinoma
- Chronic Myelomonocytic Leukemia
- Clear Cell Renal Cell Carcinoma
- de Novo Myelodysplastic Syndrome
- Metastatic Renal Cell Cancer
- Previously Treated Myelodysplastic Syndrome
- Progression of Multiple Myeloma or Plasma Cell Leukemia
- Recurrent Adult Acute Lymphoblastic Leukemia
- Recurrent Adult Acute Myeloid Leukemia
- Recurrent Adult Hodgkin Lymphoma
- Recurrent Adult Lymphoblastic Lymphoma
- Recurrent Adult Non-Hodgkin Lymphoma
- Recurrent Childhood Acute Lymphoblastic Leukemia
- Recurrent Childhood Acute Myeloid Leukemia
- Recurrent Childhood Lymphoblastic Lymphoma
- Recurrent Childhood Non-Hodgkin Lymphoma
- Refractory Anemia
- Refractory Anemia With Ringed Sideroblasts
- Refractory Childhood Hodgkin Lymphoma
- Refractory Chronic Lymphocytic Leukemia
- Renal Medullary Carcinoma
- Type 1 Papillary Renal Cell Carcinoma
- Type 2 Papillary Renal Cell Carcinoma
- Untreated Adult Acute Lymphoblastic Leukemia
- Untreated Adult Acute Myeloid Leukemia
- Untreated Childhood Acute Lymphoblastic Leukemia

## Interventions

- **DRUG:** Fludarabine Phosphate
- **RADIATION:** Total-Body Irradiation
- **PROCEDURE:** Peripheral Blood Stem Cell Transplantation
- **PROCEDURE:** Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
- **DRUG:** Cyclosporine
- **DRUG:** Mycophenolate Mofetil

## Key facts

- **NCT ID:** NCT00027820
- **Lead sponsor:** Fred Hutchinson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2001-08
- **Primary completion:** 2004-09
- **Final completion:** 2004-09-05
- **Target enrollment:** 106 (ACTUAL)
- **Last updated:** 2019-12-20

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00027820

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00027820, "Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT00027820. Licensed CC0.

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