# Comparison of Immediate and Delayed Adjuvant Chemotherapy in Treating Patients Who Have Undergone a Radical Cystectomy for Stage III or Stage IV Transitional Cell Carcinoma of the Bladder Urothelium

> **NCT00028756** · PHASE3 · COMPLETED · sponsor: **European Organisation for Research and Treatment of Cancer - EORTC** · enrollment: 285 (actual)

## Conditions studied

- Stage III Bladder Cancer
- Stage IV Bladder Cancer
- Transitional Cell Carcinoma of the Bladder

## Interventions

- **DRUG:** doxorubicin hydrochloride
- **DRUG:** gemcitabine hydrochloride
- **DRUG:** vinblastine sulfate
- **DRUG:** methotrexate
- **DRUG:** cisplatin
- **BIOLOGICAL:** filgrastim

## Key facts

- **NCT ID:** NCT00028756
- **Lead sponsor:** European Organisation for Research and Treatment of Cancer - EORTC
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2001-10
- **Primary completion:** 2014-01
- **Final completion:** 2014-07
- **Target enrollment:** 285 (ACTUAL)
- **Last updated:** 2016-08-02

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00028756

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00028756, "Comparison of Immediate and Delayed Adjuvant Chemotherapy in Treating Patients Who Have Undergone a Radical Cystectomy for Stage III or Stage IV Transitional Cell Carcinoma of the Bladder Urothelium". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT00028756. Licensed CC0.

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