# Chemotherapy, Imatinib Mesylate, and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

> **NCT00039377** · PHASE2 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 58 (actual)

## Conditions studied

- Adult Acute Lymphoblastic Leukemia in Remission

## Interventions

- **DRUG:** imatinib mesylate
- **DRUG:** methotrexate
- **DRUG:** vincristine sulfate
- **DRUG:** leucovorin calcium
- **PROCEDURE:** peripheral blood stem cell transplantation
- **PROCEDURE:** autologous hematopoietic stem cell transplantation
- **PROCEDURE:** allogeneic hematopoietic stem cell transplantation
- **RADIATION:** total-body irradiation
- **DRUG:** tacrolimus
- **BIOLOGICAL:** filgrastim
- **DRUG:** etoposide
- **DRUG:** cyclophosphamide
- **DRUG:** cytarabine
- **OTHER:** laboratory biomarker analysis

## Key facts

- **NCT ID:** NCT00039377
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2002-04
- **Primary completion:** 2012-04
- **Final completion:** 2014-02
- **Target enrollment:** 58 (ACTUAL)
- **Last updated:** 2014-11-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00039377

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00039377, "Chemotherapy, Imatinib Mesylate, and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT00039377. Licensed CC0.

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