# Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors

> **NCT00042874** · PHASE1 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 77 (actual)

## Conditions studied

- Unspecified Adult Solid Tumor, Protocol Specific

## Interventions

- **DRUG:** alvocidib
- **DRUG:** irinotecan hydrochloride
- **DRUG:** fluorouracil
- **DRUG:** leucovorin calcium
- **OTHER:** laboratory biomarker analysis

## Key facts

- **NCT ID:** NCT00042874
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2002-05
- **Primary completion:** 2009-01
- **Final completion:** —
- **Target enrollment:** 77 (ACTUAL)
- **Last updated:** 2013-06-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00042874

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00042874, "Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT00042874. Licensed CC0.

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