# Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma

> **NCT00045721** · PHASE1 · TERMINATED · sponsor: **Pediatric Brain Tumor Consortium** · enrollment: 3 (actual)

## Conditions studied

- Brain and Central Nervous System Tumors

## Interventions

- **DRUG:** O6-benzylguanine
- **DRUG:** polifeprosan 20 with carmustine implant
- **PROCEDURE:** adjuvant therapy
- **PROCEDURE:** conventional surgery
- **PROCEDURE:** neoadjuvant therapy

## Key facts

- **NCT ID:** NCT00045721
- **Lead sponsor:** Pediatric Brain Tumor Consortium
- **Sponsor class:** NETWORK
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2003-03
- **Primary completion:** 2004-07
- **Final completion:** 2004-07
- **Target enrollment:** 3 (ACTUAL)
- **Why stopped:** Poor accrual
- **Last updated:** 2009-10-16

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00045721

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00045721, "Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT00045721. Licensed CC0.

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