# Vaccine and Chemotherapy for Previously Untreated Metastatic Breast Cancer

> **NCT00048893** · PHASE1,PHASE2 · TERMINATED · sponsor: **National Cancer Institute (NCI)** · enrollment: 37 (actual)

## Conditions studied

- Breast Neoplasms
- Metastases, Neoplasm

## Interventions

- **BIOLOGICAL:** recombinant fowlpox-CEA(6D)/TRICOM vaccine
- **BIOLOGICAL:** recombinant vaccinia-CEA(6D)/TRICOM vaccine
- **BIOLOGICAL:** filgrastim
- **BIOLOGICAL:** sargramostim
- **DRUG:** cyclophosphamide
- **DRUG:** doxorubicin hydrochloride
- **DRUG:** fludarabine phosphate
- **DRUG:** paclitaxel
- **DRUG:** Mesna

## Key facts

- **NCT ID:** NCT00048893
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2002-11
- **Primary completion:** 2011-06
- **Final completion:** 2011-06
- **Target enrollment:** 37 (ACTUAL)
- **Why stopped:** The study was closed to accrual due to very poor enrollment.
- **Last updated:** 2012-04-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00048893

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00048893, "Vaccine and Chemotherapy for Previously Untreated Metastatic Breast Cancer". Retrieved via AI Analytics 2026-09-15 from https://api.ai-analytics.org/clinical/NCT00048893. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*