# Gefitinib and Combination Chemotherapy in Treating Patients With Advanced or Recurrent Colorectal Cancer

> **NCT00052585** · PHASE2 · TERMINATED · sponsor: **National Cancer Institute (NCI)** · enrollment: 50 (actual)

## Conditions studied

- Adenocarcinoma of the Colon
- Adenocarcinoma of the Rectum
- Mucinous Adenocarcinoma of the Colon
- Mucinous Adenocarcinoma of the Rectum
- Recurrent Colon Cancer
- Recurrent Rectal Cancer
- Signet Ring Adenocarcinoma of the Colon
- Signet Ring Adenocarcinoma of the Rectum
- Stage IV Colon Cancer
- Stage IV Rectal Cancer

## Interventions

- **DRUG:** irinotecan hydrochloride
- **DRUG:** gefitinib
- **DRUG:** leucovorin calcium
- **DRUG:** fluorouracil

## Key facts

- **NCT ID:** NCT00052585
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2002-10
- **Primary completion:** 2004-11
- **Final completion:** —
- **Target enrollment:** 50 (ACTUAL)
- **Why stopped:** Administratively complete.
- **Last updated:** 2013-01-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00052585

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00052585, "Gefitinib and Combination Chemotherapy in Treating Patients With Advanced or Recurrent Colorectal Cancer". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00052585. Licensed CC0.

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