# Isotretinoin, Interferon Alfa, and Vitamin E in Treating Patients With Stage III or Stage IV Head and Neck Cancer

> **NCT00054561** · PHASE3 · COMPLETED · sponsor: **Eastern Cooperative Oncology Group**

## Conditions studied

- Head and Neck Cancer

## Interventions

- **BIOLOGICAL:** recombinant interferon alfa
- **DIETARY_SUPPLEMENT:** vitamin E
- **DRUG:** isotretinoin
- **PROCEDURE:** adjuvant therapy

## Key facts

- **NCT ID:** NCT00054561
- **Lead sponsor:** Eastern Cooperative Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2003-11-26
- **Primary completion:** 2004-12
- **Final completion:** 2009-05-01
- **Target enrollment:** — (—)
- **Last updated:** 2023-06-15

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00054561

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00054561, "Isotretinoin, Interferon Alfa, and Vitamin E in Treating Patients With Stage III or Stage IV Head and Neck Cancer". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00054561. Licensed CC0.

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