# Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer

> **NCT00068692** · PHASE3 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 225 (actual)

## Conditions studied

- Rectal Mucinous Adenocarcinoma
- Rectal Signet Ring Cell Adenocarcinoma
- Recurrent Rectal Carcinoma
- Stage IIA Rectal Cancer AJCC v7
- Stage IIB Rectal Cancer AJCC v7
- Stage IIC Rectal Cancer AJCC v7
- Stage IIIA Rectal Cancer AJCC v7
- Stage IIIB Rectal Cancer AJCC v7
- Stage IIIC Rectal Cancer AJCC v7
- Stage IVA Rectal Cancer AJCC v7
- Stage IVB Rectal Cancer AJCC v7

## Interventions

- **RADIATION:** Radiotherapy
- **DRUG:** Fluorouracil
- **DRUG:** Leucovorin Calcium
- **DRUG:** Oxaliplatin
- **DRUG:** Irinotecan

## Key facts

- **NCT ID:** NCT00068692
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2003-10-15
- **Primary completion:** 2016-11-15
- **Final completion:** 2016-11-15
- **Target enrollment:** 225 (ACTUAL)
- **Last updated:** 2018-12-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00068692

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00068692, "Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT00068692. Licensed CC0.

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