# Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer

> **NCT00081289** · PHASE2 · COMPLETED · sponsor: **Radiation Therapy Oncology Group** · enrollment: 146 (actual)

## Conditions studied

- Colorectal Cancer

## Interventions

- **RADIATION:** Radiation Therapy
- **DRUG:** Capecitabine 1650 mg/m^2/day
- **DRUG:** Capecitabine 1200 mg/m^2/day
- **DRUG:** Irinotecan
- **DRUG:** Oxaliplatin
- **PROCEDURE:** Surgery
- **DRUG:** Folinic Acid
- **DRUG:** Fluorouracil
- **DRUG:** Oxaliplatin

## Key facts

- **NCT ID:** NCT00081289
- **Lead sponsor:** Radiation Therapy Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-03
- **Primary completion:** 2011-05
- **Final completion:** 2016-12
- **Target enrollment:** 146 (ACTUAL)
- **Last updated:** 2020-02-27

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00081289

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00081289, "Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer". Retrieved via AI Analytics 2026-07-12 from https://api.ai-analytics.org/clinical/NCT00081289. Licensed CC0.

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