# Efficacy and Safety of Seroquel Plus Mood Stabilizer in the Maintenance of Bipolar I Disorder

> **NCT00081380** · PHASE3 · COMPLETED · sponsor: **AstraZeneca** · enrollment: 710 (—)

## Conditions studied

- Bipolar Disorder

## Interventions

- **DRUG:** Seroquel®, quetiapine fumarate (atypical antipsychotic)
- **DRUG:** lithium (mood stabilizer)
- **DRUG:** divalproex (mood stabilizer)

## Key facts

- **NCT ID:** NCT00081380
- **Lead sponsor:** AstraZeneca
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-03
- **Primary completion:** —
- **Final completion:** 2006-09
- **Target enrollment:** 710 (—)
- **Last updated:** 2008-12-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00081380

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00081380, "Efficacy and Safety of Seroquel Plus Mood Stabilizer in the Maintenance of Bipolar I Disorder". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00081380. Licensed CC0.

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