# Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma

> **NCT00085735** · PHASE3 · COMPLETED · sponsor: **Children's Oncology Group** · enrollment: 549 (actual)

## Conditions studied

- Medulloblastoma

## Interventions

- **DRUG:** Cisplatin
- **RADIATION:** Craniospinal Irradiation
- **DRUG:** Cyclophosphamide
- **RADIATION:** Involved-Field Radiation Therapy
- **OTHER:** Laboratory Biomarker Analysis
- **DRUG:** Lomustine
- **OTHER:** Quality-of-Life Assessment
- **RADIATION:** Radiation Therapy
- **DRUG:** Vincristine Sulfate

## Key facts

- **NCT ID:** NCT00085735
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-04-30
- **Primary completion:** 2016-03-31
- **Final completion:** 2024-12-31
- **Target enrollment:** 549 (ACTUAL)
- **Last updated:** 2025-01-14

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00085735

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00085735, "Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00085735. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*