# Effect of Metreleptin Therapy in the Treatment of Severe Insulin Resistance

> **NCT00085982** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)** · enrollment: 11 (actual)

## Conditions studied

- Severe Insulin Resistance

## Interventions

- **DRUG:** Metreleptin

## Key facts

- **NCT ID:** NCT00085982
- **Lead sponsor:** National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2003-08-21
- **Primary completion:** 2019-10-23
- **Final completion:** 2030-01-01
- **Target enrollment:** 11 (ACTUAL)
- **Last updated:** 2025-01-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00085982

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00085982, "Effect of Metreleptin Therapy in the Treatment of Severe Insulin Resistance". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00085982. Licensed CC0.

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