# Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral Contraceptives

> **NCT00089414** · PHASE2 · TERMINATED · sponsor: **National Institute of Mental Health (NIMH)** · enrollment: 5 (actual)

## Conditions studied

- Premenstrual Syndrome
- PMS
- Premenstrual Dysphoric Disorder
- PMDD
- Depression

## Interventions

- **DRUG:** Ethinyl Estradiol/Drospirenone
- **DRUG:** Placebo
- **DRUG:** CDB 2914

## Key facts

- **NCT ID:** NCT00089414
- **Lead sponsor:** National Institute of Mental Health (NIMH)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2004-07
- **Primary completion:** 2010-06
- **Final completion:** 2010-06
- **Target enrollment:** 5 (ACTUAL)
- **Why stopped:** Informed by manufacturer that CDB-2914 crosses blood-brain barrier invalidating Arm #3 of protocol.
- **Last updated:** 2017-08-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00089414

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00089414, "Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral Contraceptives". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT00089414. Licensed CC0.

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