Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors

NCT00095940 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

COMPLETED

Status

52

Enrollment

NIH

Sponsor class

Conditions

Recurrent Childhood Anaplastic Astrocytoma
Recurrent Childhood Brain Stem Glioma
Recurrent Childhood Ependymoma
Recurrent Childhood Giant Cell Glioblastoma
Recurrent Childhood Glioblastoma
Recurrent Childhood Gliosarcoma
Recurrent Childhood Medulloblastoma
Recurrent Childhood Oligodendroglioma

Interventions

DRUG: lapatinib ditosylate
PROCEDURE: therapeutic conventional surgery
OTHER: laboratory biomarker analysis
OTHER: pharmacological study
PROCEDURE: positron emission tomography
PROCEDURE: magnetic resonance imaging

Sponsor

National Cancer Institute (NCI)