# Lapatinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

> **NCT00098631** · PHASE2 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 88 (estimated)

## Conditions studied

- Metastatic Squamous Neck Cancer With Occult Primary
- Recurrent Metastatic Squamous Neck Cancer With Occult Primary
- Recurrent Squamous Cell Carcinoma of the Hypopharynx
- Recurrent Squamous Cell Carcinoma of the Larynx
- Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity
- Recurrent Squamous Cell Carcinoma of the Nasopharynx
- Recurrent Squamous Cell Carcinoma of the Oropharynx
- Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
- Salivary Gland Squamous Cell Carcinoma
- Stage IV Squamous Cell Carcinoma of the Hypopharynx
- Stage IV Squamous Cell Carcinoma of the Larynx
- Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity
- Stage IV Squamous Cell Carcinoma of the Nasopharynx
- Stage IV Squamous Cell Carcinoma of the Oropharynx
- Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
- Untreated Metastatic Squamous Neck Cancer With Occult Primary

## Interventions

- **DRUG:** lapatinib ditosylate
- **OTHER:** laboratory biomarker analysis

## Key facts

- **NCT ID:** NCT00098631
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-10
- **Primary completion:** 2006-12
- **Final completion:** —
- **Target enrollment:** 88 (ESTIMATED)
- **Last updated:** 2014-01-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00098631

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00098631, "Lapatinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer". Retrieved via AI Analytics 2026-07-10 from https://api.ai-analytics.org/clinical/NCT00098631. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*