# MK0457 (an Aurora Kinase Inhibitor) Study in Patients With Advanced Colorectal Cancer and Other Advanced Solid Tumors (0457-001)

> **NCT00099346** · PHASE1 · TERMINATED · sponsor: **Merck Sharp & Dohme LLC**

## Conditions studied

- Colorectal Cancer
- Advanced Solid Tumors

## Interventions

- **DRUG:** MK0457, VX-680 (Aurora Kinase Inhibitor)

## Key facts

- **NCT ID:** NCT00099346
- **Lead sponsor:** Merck Sharp & Dohme LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2005-01
- **Primary completion:** 2007-04
- **Final completion:** 2007-04
- **Target enrollment:** — (—)
- **Last updated:** 2015-06-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00099346

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00099346, "MK0457 (an Aurora Kinase Inhibitor) Study in Patients With Advanced Colorectal Cancer and Other Advanced Solid Tumors (0457-001)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00099346. Licensed CC0.

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