# Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors

> **NCT00110032** · PHASE1 · TERMINATED · sponsor: **National Cancer Institute (NCI)** · enrollment: 46 (actual)

## Conditions studied

- Adult Anaplastic Astrocytoma
- Adult Anaplastic Ependymoma
- Adult Anaplastic Oligodendroglioma
- Adult Brain Stem Glioma
- Adult Central Nervous System Germ Cell Tumor
- Adult Choroid Plexus Tumor
- Adult Craniopharyngioma
- Adult Diffuse Astrocytoma
- Adult Ependymoblastoma
- Adult Ependymoma
- Adult Giant Cell Glioblastoma
- Adult Glioblastoma
- Adult Gliosarcoma
- Adult Grade I Meningioma
- Adult Grade II Meningioma
- Adult Grade III Meningioma
- Adult Medulloblastoma
- Adult Meningeal Hemangiopericytoma
- Adult Mixed Glioma
- Adult Myxopapillary Ependymoma
- Adult Oligodendroglioma
- Adult Pilocytic Astrocytoma
- Adult Pineoblastoma
- Adult Pineocytoma
- Adult Subependymoma
- Adult Supratentorial Primitive Neuroectodermal Tumor (PNET)
- Meningeal Melanocytoma

## Interventions

- **DRUG:** EF5
- **PROCEDURE:** conventional surgery
- **PROCEDURE:** positron emission tomography
- **RADIATION:** fluorine F 18 EF5
- **OTHER:** pharmacological study

## Key facts

- **NCT ID:** NCT00110032
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2005-06
- **Primary completion:** 2007-01
- **Final completion:** —
- **Target enrollment:** 46 (ACTUAL)
- **Why stopped:** Administratively complete.
- **Last updated:** 2013-01-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00110032

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00110032, "Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT00110032. Licensed CC0.

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