# S0307 Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer.

> **NCT00127205** · PHASE3 · COMPLETED · sponsor: **SWOG Cancer Research Network** · enrollment: 6097 (actual)

## Conditions studied

- Breast Cancer

## Interventions

- **DRUG:** clodronate disodium
- **DRUG:** ibandronate sodium
- **DRUG:** zoledronic acid

## Key facts

- **NCT ID:** NCT00127205
- **Lead sponsor:** SWOG Cancer Research Network
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-07
- **Primary completion:** 2017-12
- **Final completion:** 2021-03-29
- **Target enrollment:** 6097 (ACTUAL)
- **Last updated:** 2021-07-02

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00127205

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00127205, "S0307 Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer.". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT00127205. Licensed CC0.

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