# Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury

> **NCT00127491** · NA · COMPLETED · sponsor: **Beth Israel Deaconess Medical Center** · enrollment: 63 (actual)

## Conditions studied

- Acute Lung Injury
- Acute Respiratory Distress Syndrome

## Interventions

- **PROCEDURE:** Placement of an esophageal balloon measurements
- **OTHER:** Low tidal volume ventilation
- **OTHER:** Transpulmonary pressure-directed ventilation (EPVent)

## Key facts

- **NCT ID:** NCT00127491
- **Lead sponsor:** Beth Israel Deaconess Medical Center
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-05
- **Primary completion:** 2007-08
- **Final completion:** 2010-05
- **Target enrollment:** 63 (ACTUAL)
- **Last updated:** 2017-02-27

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00127491

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00127491, "Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT00127491. Licensed CC0.

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