# Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain

> **NCT00129246** · PHASE1,PHASE2 · COMPLETED · sponsor: **Yale University** · enrollment: 40 (actual)

## Conditions studied

- Smoking
- Nicotine Dependence

## Interventions

- **DRUG:** Naltrexone
- **DRUG:** Bupropion

## Key facts

- **NCT ID:** NCT00129246
- **Lead sponsor:** Yale University
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-12
- **Primary completion:** —
- **Final completion:** 2005-12
- **Target enrollment:** 40 (ACTUAL)
- **Last updated:** 2020-12-03

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00129246

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00129246, "Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00129246. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*