# Seroquel in Acute Mania: Study to Investigate if Valproate Add-On Therapy is Superior to Quetiapine Monotherapy in Acutely Manic Patients

> **NCT00139074** · PHASE4 · TERMINATED · sponsor: **AstraZeneca** · enrollment: 17 (actual)

## Conditions studied

- Bipolar Disorder

## Interventions

- **DRUG:** Quetiapine fumarate
- **DRUG:** sodium valproate

## Key facts

- **NCT ID:** NCT00139074
- **Lead sponsor:** AstraZeneca
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2005-07
- **Primary completion:** 2006-06
- **Final completion:** 2006-06
- **Target enrollment:** 17 (ACTUAL)
- **Why stopped:** terminated due to very low recruitment rate (27 June 2006)
- **Last updated:** 2013-01-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00139074

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00139074, "Seroquel in Acute Mania: Study to Investigate if Valproate Add-On Therapy is Superior to Quetiapine Monotherapy in Acutely Manic Patients". Retrieved via AI Analytics 2026-06-30 from https://api.ai-analytics.org/clinical/NCT00139074. Licensed CC0.

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