# Renin-angiotensin-aldosterone System (RAAS), Inflammation, and Post-Operative Atrial Fibrillation (AF)

> **NCT00141778** · PHASE2,PHASE3 · COMPLETED · sponsor: **Vanderbilt University** · enrollment: 455 (actual)

## Conditions studied

- Atrial Fibrillation

## Interventions

- **DRUG:** Placebo
- **DRUG:** Ramipril
- **DRUG:** Spironolactone

## Key facts

- **NCT ID:** NCT00141778
- **Lead sponsor:** Vanderbilt University
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-04
- **Primary completion:** 2010-07
- **Final completion:** 2010-08
- **Target enrollment:** 455 (ACTUAL)
- **Last updated:** 2013-03-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00141778

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00141778, "Renin-angiotensin-aldosterone System (RAAS), Inflammation, and Post-Operative Atrial Fibrillation (AF)". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT00141778. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*