# Prednisone Timed-Release Tablet (TRT) Study: Modified-Release (MR) Formulation of Prednisone Compared to Standard Immediate-Release (IR) Prednisone in Participants With Rheumatoid Arthritis

> **NCT00146640** · PHASE3 · COMPLETED · sponsor: **Merck KGaA, Darmstadt, Germany** · enrollment: 288 (actual)

## Conditions studied

- Rheumatoid Arthritis

## Interventions

- **DRUG:** MR Prednisone
- **DRUG:** IR Prednisone
- **DRUG:** Placebo - MR Prednisone
- **DRUG:** Placebo - IR Prednisone

## Key facts

- **NCT ID:** NCT00146640
- **Lead sponsor:** Merck KGaA, Darmstadt, Germany
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-08-31
- **Primary completion:** 2007-01-31
- **Final completion:** 2007-01-31
- **Target enrollment:** 288 (ACTUAL)
- **Last updated:** 2018-07-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00146640

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00146640, "Prednisone Timed-Release Tablet (TRT) Study: Modified-Release (MR) Formulation of Prednisone Compared to Standard Immediate-Release (IR) Prednisone in Participants With Rheumatoid Arthritis". Retrieved via AI Analytics 2026-07-17 from https://api.ai-analytics.org/clinical/NCT00146640. Licensed CC0.

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