# Beta-carotene and Alpha-tocopherol Chemoprevention of Second Primary Malignancies in Head and Neck Cancer Patients

> **NCT00169845** · PHASE3 · COMPLETED · sponsor: **Laval University** · enrollment: 540 (actual)

## Conditions studied

- Neoplasms

## Interventions

- **DIETARY_SUPPLEMENT:** Alpha-Tocopherol and Beta-Carotene
- **DIETARY_SUPPLEMENT:** Placebo

## Key facts

- **NCT ID:** NCT00169845
- **Lead sponsor:** Laval University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1994-10
- **Primary completion:** 2003-06
- **Final completion:** 2018-03
- **Target enrollment:** 540 (ACTUAL)
- **Last updated:** 2018-03-14

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00169845

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00169845, "Beta-carotene and Alpha-tocopherol Chemoprevention of Second Primary Malignancies in Head and Neck Cancer Patients". Retrieved via AI Analytics 2026-07-08 from https://api.ai-analytics.org/clinical/NCT00169845. Licensed CC0.

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