# Combination Chemotherapy With or Without Trastuzumab Followed By an Autologous Stem Cell Transplant and Radiation Therapy in Treating Patients With Stage III or Stage IV Breast Cancer

> **NCT00182793** · PHASE2 · COMPLETED · sponsor: **City of Hope Medical Center** · enrollment: 32 (actual)

## Conditions studied

- Breast Cancer

## Interventions

- **BIOLOGICAL:** trastuzumab
- **DRUG:** carboplatin
- **DRUG:** cyclophosphamide
- **DRUG:** melphalan
- **DRUG:** thiotepa
- **PROCEDURE:** adjuvant therapy
- **PROCEDURE:** autologous-autologous tandem hematopoietic stem cell transplantation
- **PROCEDURE:** bone marrow ablation with stem cell support
- **RADIATION:** radiation therapy

## Key facts

- **NCT ID:** NCT00182793
- **Lead sponsor:** City of Hope Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-07
- **Primary completion:** 2014-10
- **Final completion:** 2014-10
- **Target enrollment:** 32 (ACTUAL)
- **Last updated:** 2017-02-23

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00182793

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00182793, "Combination Chemotherapy With or Without Trastuzumab Followed By an Autologous Stem Cell Transplant and Radiation Therapy in Treating Patients With Stage III or Stage IV Breast Cancer". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT00182793. Licensed CC0.

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