# Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma

> **NCT00186888** · PHASE3 · COMPLETED · sponsor: **St. Jude Children's Research Hospital** · enrollment: 107 (actual)

## Conditions studied

- Retinoblastoma
- Retinal Neoplasm

## Interventions

- **PROCEDURE:** Enucleation
- **DRUG:** Vincristine, Carboplatin
- **PROCEDURE:** Focal Therapies
- **RADIATION:** External Beam Radiation
- **DRUG:** Vincristine and Topotecan
- **DRUG:** Vincristine + Carboplatin + Etoposide
- **DRUG:** vincristine, cyclophosphamide, and doxorubicin
- **DRUG:** Vincristine, Carboplatin and Etoposide
- **PROCEDURE:** Periocular carboplatin
- **OTHER:** G-CSF

## Key facts

- **NCT ID:** NCT00186888
- **Lead sponsor:** St. Jude Children's Research Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-04-07
- **Primary completion:** 2013-11
- **Final completion:** 2024-11-12
- **Target enrollment:** 107 (ACTUAL)
- **Last updated:** 2025-09-04

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00186888

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00186888, "Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma". Retrieved via AI Analytics 2026-07-28 from https://api.ai-analytics.org/clinical/NCT00186888. Licensed CC0.

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