Combination Chemotherapy and Filgrastim Before Surgery in Treating Patients With HER2-Positive Breast Cancer That Can Be Removed By Surgery
Conditions
- Estrogen Receptor-negative Breast Cancer
- Estrogen Receptor-positive Breast Cancer
- HER2-positive Breast Cancer
- Progesterone Receptor-negative Breast Cancer
- Progesterone Receptor-positive Breast Cancer
- Stage IA Breast Cancer
- Stage IB Breast Cancer
- Stage II Breast Cancer
- Stage IIIA Breast Cancer
Interventions
- DRUG: doxorubicin hydrochloride
- DRUG: cyclophosphamide
- DRUG: paclitaxel
- BIOLOGICAL: filgrastim
- DRUG: capecitabine
- DRUG: methotrexate
- DRUG: vinorelbine tartrate
- PROCEDURE: needle biopsy
- PROCEDURE: therapeutic conventional surgery
- OTHER: immunohistochemistry staining method
- BIOLOGICAL: trastuzumab
- DRUG: tamoxifen citrate
- DRUG: letrozole
- OTHER: laboratory biomarker analysis
Sponsor
University of Washington
Collaborators