# Study Comparing Etanercept and Methotrexate vs. Methotrexate Alone in Rheumatoid Arthritis

> **NCT00195494** · PHASE4 · COMPLETED · sponsor: **Wyeth is now a wholly owned subsidiary of Pfizer** · enrollment: 542 (actual)

## Conditions studied

- Rheumatoid Arthritis

## Interventions

- **DRUG:** Etanercept
- **DRUG:** Methotrexate
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT00195494
- **Lead sponsor:** Wyeth is now a wholly owned subsidiary of Pfizer
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-11
- **Primary completion:** 2008-03
- **Final completion:** 2008-03
- **Target enrollment:** 542 (ACTUAL)
- **Last updated:** 2012-09-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00195494

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00195494, "Study Comparing Etanercept and Methotrexate vs. Methotrexate Alone in Rheumatoid Arthritis". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT00195494. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*